The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2025
Filed:
Mar. 27, 2020
Arcus Biosciences, Inc., Hayward, CA (US);
Amy Elizabeth Anderson, San Mateo, CA (US);
Devika Ashok, Belmont, CA (US);
Daniel M. DiRenzo, Palo Alto, CA (US);
Akshata R. Udyavar, Foster City, CA (US);
Matthew J. Walters, Pacifica, CA (US);
Stephen W. Young, Palomar Park, CA (US);
ARCUS BIOSCIENCES, INC., Hayward, CA (US);
Abstract
The present disclosure provides methods of treating a cancer in a subject having an established adenosine fingerprint. An established adenosine fingerprint includes assessing the blood concentration of one or more adenosine machinery proteins, assessing the enzymatic activity of one or more adenosine machinery proteins, and/or assessing the tumor expression level of adenosine machinery proteins. The methods disclosed herein include administering to said subjects a therapeutic agent selected from the group consisting of an agent targeting the extracellular production of adenosine, and an agent antagonizing the activation by adenosine of one of its receptors.