The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2025
Filed:
Dec. 10, 2019
The Regents of the University of California, Oakland, CA (US);
Case Western Reserve University, Cleveland, OH (US);
Sarah Knox, San Francisco, CA (US);
Chelsea S. Bahney, Edwards, CO (US);
Eben Alsberg, Chicago, IL (US);
Oju Jeon, Broadview Heights, OH (US);
Case Western Reserve University, Cleveland, OH (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
A method is provided for promoting salivary gland regeneration in a subject in need thereof comprising administering to acinar progenitor cells of the salivary gland at least one of a cholinergic agonist or muscarinic agonist to promote acinar cell generation. In particular, formulations comprising a muscarinic agonist such as cevimeline encapsulated in an alginate hydrogel can be formulated for local administration to a salivary gland and used in treatment of xerostomia.