The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2025
Filed:
May. 30, 2020
W. L. Gore & Associates, Inc., Newark, DE (US);
Viacyte, Inc., San Diego, CA (US);
Timothy M. Bruhn, Newark, DE (US);
Kevin D'Amour, San Diego, CA (US);
Christopher Folk, San Diego, CA (US);
Craig McGreevy, San Diego, CA (US);
Laura Martinson, San Diego, CA (US);
Scott A. Ritrovato, Newark, DE (US);
Greg Rusch, Newark, DE (US);
Michael Scott, San Diego, CA (US);
Lauren R. Zambotti, Newark, DE (US);
Qiang (John) Zhang, San Diego, CA (US);
Joseph Kakkassery, San Diego, CA (US);
W. L. Gore & Associates, Inc., Newark, DE (US);
ViaCyte, Inc., San Diego, CA (US);
Abstract
A biocompatible membrane composite including a cell impermeable layer and a mitigation layer is provided. The cell impermeable layer is impervious to vascular ingrowth and prevents cellular contact from the host. Additionally, the mitigation layer includes solid features. In at least one embodiment, mitigation layer has therein bonded solid features. In some embodiments, the cell impermeable layer and the mitigation layer are intimately bonded or otherwise connected to each other to form a composite layer having a tight/open structure. A reinforcing component may optionally be positioned external to or within the biocompatible membrane composite to provide support to and prevent distortion. The biocompatible membrane composite may be used in or to form a device for encapsulating biological entities, including, but not limited to, pancreatic lineage type cells such as pancreatic progenitors.