The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 20, 2025

Filed:

Jun. 03, 2020
Applicant:

Nantbio, Inc., Culver City, CA (US);

Inventors:

Clifford Anders Olson, Long Beach, CA (US);

Kayvan Niazi, Agoura Hills, CA (US);

Nicholas J. Witchey, Laguna Hills, CA (US);

Wael Tadros, Los Angeles, CA (US);

Assignee:

NantBio, Inc., Culver City, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G16B 5/00 (2019.01); G16B 25/10 (2019.01);
U.S. Cl.
CPC ...
G16B 5/00 (2019.02); G16B 25/10 (2019.02);
Abstract

Described herein are methods of making recombinant cells using an in silico-generated pathway map of an endogenous pathway in a cell of interest to determine, in silico, a predicted effect of incorporating a recombinant nucleic acid into the endogenous pathway; and based on the predicted effect, incorporating the recombinant nucleic acid into the endogenous pathway in the cell of interest such that activation of the endogenous pathway regulates expression of the recombinant nucleic acid.


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