The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 20, 2025

Filed:

Jun. 22, 2021
Applicant:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Inventors:

Jean-Pierre Bolliger, Lucerne, CH;

Rik Harbers, Zug, CH;

Rolf Knobel, Zug, CH;

Assignee:

ROCHE DIAGNOSTICS OPERATIONS, INC., Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/72 (2006.01); G01N 21/25 (2006.01); G01N 21/51 (2006.01); G01N 21/59 (2006.01); G01N 33/92 (2006.01);
U.S. Cl.
CPC ...
G01N 33/721 (2013.01); G01N 21/251 (2013.01); G01N 21/51 (2013.01); G01N 21/59 (2013.01); G01N 33/728 (2013.01); G01N 33/92 (2013.01);
Abstract

A method of determining a level of interference with a photometric in-vitro diagnostic assay and an in-vitro diagnostic analyzer for carrying out the method are described. An aliquot of a sample is treated with at least one reagent to obtain a sample/reagent mixture and subjecting the sample/reagent mixture to a photometric measurement in order to obtain a result of the in-vitro diagnostic assay, and during the same photometric measurement determining a preliminary level of interference by semi-quantitatively determining one or more interfering substances in the same sample/reaction mixture. A separate photometric measurement of another aliquot of the same sample either undiluted or diluted with a liquid other than a reagent is triggered in order to determine an effective level of interference by quantitatively determining the one or more interfering substances, only upon determining a preliminary level of interference above a predetermined threshold.


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