The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2025
Filed:
Feb. 03, 2022
Applicant:
Cedars-sinai Medical Center, Los Angeles, CA (US);
Inventors:
Maya Koronyo, Los Angeles, CA (US);
Haoshen Shi, Los Angeles, CA (US);
Yosef Koronyo, Los Angeles, CA (US);
Keith L. Black, Los Angeles, CA (US);
Assignee:
Cedars-Sinai Medical Center, Los Angeles, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06K 9/00 (2022.01); A61B 3/00 (2006.01); A61B 3/10 (2006.01); A61B 3/12 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6896 (2013.01); A61B 3/0025 (2013.01); A61B 3/102 (2013.01); A61B 3/12 (2013.01); G01N 2800/2821 (2013.01);
Abstract
The present invention describes a method for the detection, diagnosis and monitoring of cognitive impairment and Alzheimer's disease. The method involves the detection of pericyte loss and deficiency in PDGFRβ, alone or in combination with retinal vascular Aβ deposits. The method also involves detecting an alteration in blood-retinal barrier (BRB) cell tight junction.