The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 20, 2025

Filed:

Dec. 20, 2023
Applicant:

Tetmedical, Inc., Fair Haven, NJ (US);

Inventors:

David R. Fischell, Fair Haven, NJ (US);

Roy Cohen, Cortland, NY (US);

Alexander J. Travis, Ithaca, NY (US);

Furkat Mukhtarov, Ithaca, NY (US);

John Mcguire Jaicks, Alexandria, VA (US);

Assignee:

TETmedical, Inc., Fair Haven, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/52 (2006.01); A61J 1/05 (2006.01); C12Q 1/527 (2006.01); G01N 21/76 (2006.01); G01N 33/543 (2006.01); G01N 33/573 (2006.01);
U.S. Cl.
CPC ...
G01N 33/573 (2013.01); A61J 1/05 (2013.01); C12Q 1/52 (2013.01); C12Q 1/527 (2013.01); G01N 21/76 (2013.01); G01N 33/54346 (2013.01); G01N 2333/91188 (2013.01); G01N 2333/988 (2013.01); G01N 2800/28 (2013.01);
Abstract

A coupled enzyme reaction point of care assay system detects and measures an active enzyme biomarker from a patient's blood sample. The assay system has a point of care blood collector for collecting blood into a blood collection vial. A biomarker detection mechanism has at least three fluid flow entities. Each fluid flow entity has a fluid input zone and a corresponding reaction zone. The fluid flow entities include a test strip, a negative control strip and a positive control strip. The reaction zones include components from a multiplicity of substrates, co-factors, buffers and cryoprotectants, and a multiplicity of tethered enzymes. At least one of the tethered enzymes is an enzyme that produces luminescence. The tethered enzymes are adapted to react to a constituent which may be a biomarker. A photonic luminescence reader measures light emitted from an active enzyme biomarker present in the patient's blood.


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