The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2025
Filed:
Oct. 18, 2018
Ohio State Innovation Foundation, Columbus, OH (US);
Ayush Garg, Columbus, OH (US);
Travis Jones, Columbus, OH (US);
Sarah Bushman, Columbus, OH (US);
Jessica Ferree, Columbus, OH (US);
Vishwanath Subramaniam, Columbus, OH (US);
Jonathan Song, Columbus, OH (US);
Deepa Subramaniam, Columbus, OH (US);
Ohio State Innovation Foundation, Columbus, OH (US);
Abstract
Disclosed herein are devices and methods for measuring the effect of chemokines and electric fields on cell migration. This approach is inherently non-contact and does not require injection of current. For example, disclosed herein is a device for assessing cell migration that comprises a cell migration chamber and an electromagnet positioned to produce a uniform electric field across the length of the chamber. Also disclosed is a method for assaying a cell that involves loading cells into the disclosed device along with a chemokine in an amount to produce a chemokine gradient, activating the electromagnet to produce an electric field across the cell migration chamber, and imaging the cells to measure the dual effect of the chemokine and the electric field on the cells.