The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2025
Filed:
Apr. 26, 2019
Cedars-sinai Medical Center, Los Angeles, CA (US);
Prometheus Biosciences, Inc., San Diego, CA (US);
Janine Bilsborough, Simi Valley, CA (US);
Dermot P. McGovern, Los Angeles, CA (US);
Stephan Targan, Los Angeles, CA (US);
Alka Potdar, Cumming, CA (US);
Jeffry D. Watkins, Encinitas, CA (US);
Cindy T. Dickerson, Encinitas, CA (US);
Cedars-Sinai Medical Center, Los Angeles, CA (US);
Prometheus Biosciences, Inc., San Diego, CA (US);
Abstract
Described herein are methods and systems for identifying subjects suitable for treatment with an inhibitor of CD30L activity or expression, such as an anti-CD30L antibody. Methods and systems disclosed herein identify subjects suitable for treatment based on a presence of a genotype that is indicative of a disease or condition in the subject for which an inhibitor of CD30L is a suitable treatment. Exemplary conditions include both Crohns disease and primary sclerosing cholangitis. Compositions used to detect the genotypes described herein, and methods of using them are also provided.