The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2025
Filed:
Sep. 27, 2019
Jecho Institute, Co., Ltd., Shanghai, CN;
Jecho Laboratories, Inc., Frederick, MD (US);
Jianwei Zhu, Shanghai, CN;
Jing Wang, Shanghai, CN;
Lei Han, Shanghai, CN;
Junsheng Chen, Shanghai, CN;
Yueqing Xie, Shanghai, CN;
Hua Jiang, Shanghai, CN;
JECHO LABORATORIES, INC., Frederick, MD (US);
JECHO INSTITUTE, CO., LTD., Shanghai, CN;
Abstract
A polypeptide composition, and methods of making the same, may include a first polypeptide and a second polypeptide, wherein the first polypeptide comprise a first toxin fragment and a first intein fragment, the second polypeptide comprise a second toxin fragment and a second intein fragment, the first polypeptide is different from the second polypeptide; the first toxin fragment and the second toxin fragment are non-biotoxic; the first polypeptide and the second polypeptide may make the first toxin fragment and the second toxin fragment into biotoxic toxins by an interaction of the first intein fragment and the second intein fragment. Kits may include such first and second polypeptides, and such compositions and kits may be used in treating tumors.