The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2025
Filed:
Jul. 10, 2024
East China University of Science and Technology, Shanghai, CN;
Zhiqian Guo, Shanghai, CN;
Juan Li, Shanghai, CN;
Yutao Zhang, Shanghai, CN;
Yao Lu, Shanghai, CN;
Chenxu Yan, Shanghai, CN;
Meiling Zhao, Shanghai, CN;
Xiuyan Zhao, Shanghai, CN;
Weihong Zhu, Shanghai, CN;
East China University of Science and Technology, Shanghai, CN;
Abstract
A luminescent probe and its preparation method and application are provided. The luminescent probe has a steric hindrance group Rof aliphatic hydrocarbon structure such as adamantane or norborneol, a detection group Rof nitrobenzyl and its derivative structure, an electron-withdrawing group Rcontaining cyano group and an electron-donating group methoxy group. In the presence of HSA or BSA, the detection group is cut off to form a parent structure that exposes atomic oxygen anions and is activated under external light irradiation, the luminescent probe can be used in solution or cells, when detecting HSA or BSA, the luminescent probe has obvious chemiluminescence characteristics, which can sensitively distinguish HSA and BSA, quantitatively analyze HSA and BSA, and determine the mixing ratio of HSA and BSA at the same time, and the luminescent probe has been successfully used for cell fluorescence imaging.