The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2025
Filed:
Dec. 14, 2018
Applicant:
Autolus Limited, London, GB;
Inventors:
Martin Pulé, London, GB;
Marco Della Peruta, London, GB;
Assignee:
AUTOLUS LIMITED, London, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/42 (2025.01); C07K 14/725 (2006.01); C07K 16/30 (2006.01); C07K 19/00 (2006.01); C12N 5/00 (2006.01); C12N 5/0783 (2010.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70578 (2013.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/4204 (2025.01); A61K 40/4211 (2025.01); A61K 40/4215 (2025.01); A61K 40/4258 (2025.01); C07K 14/7051 (2013.01); C07K 16/30 (2013.01); C07K 19/00 (2013.01); C12N 5/0636 (2013.01); C07K 16/2803 (2013.01); C07K 2319/02 (2013.01); C07K 2319/32 (2013.01);
Abstract
The present invention relates to a cell which comprises; (i) a chimeric antigen receptor (CAR) or a transgenic T-cell receptor (TCR); and (ii) a chimeric TNF receptor (TNFR) which comprises (a) a binding domain which is capable of binding a TNFR ligand; and (b) a TNFR signalling domain.