The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 20, 2025

Filed:

Nov. 18, 2024
Applicant:

Shaanxi University of Science and Technology, Shaanxi, CN;

Inventors:

Chengyuan Liang, Shaanxi, CN;

Yanzi Wang, Shaanxi, CN;

Bingxing Zhang, Shaanxi, CN;

Wen Wang, Shaanxi, CN;

Yunfei Zhang, Shaanxi, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 513/04 (2006.01); A61K 31/437 (2006.01); A61P 31/04 (2006.01); C07C 303/28 (2006.01);
U.S. Cl.
CPC ...
C07D 513/04 (2013.01); A61K 31/437 (2013.01); A61P 31/04 (2018.01); C07C 303/28 (2013.01); C07C 2603/82 (2017.05);
Abstract

A compound of formula I, a pharmaceutically acceptable salt thereof, or a solvent compound, an enantiomer, a diastereomer or a tautomer of the compound or a pharmaceutically acceptable salt thereof is disclosed, wherein R is a phenyl substituted with an electron withdrawing group or a phenyl substituted with an electron donating group. The pleuromutilin derivative containing a thiazolo[5,4-C]pyridine side chain in the present invention exhibits good in vitro antibacterial activity and improves the problem of poor solubility of pleuromutilin derivatives.


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