The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2025
Filed:
Dec. 12, 2024
Applicant:
Elanco Us Inc., Greenfield, IN (US);
Inventors:
Jean Marie Defauw, Greenfield, IN (US);
Guanmin Wu, Greenfield, IN (US);
Jingdan Hu, Greenfield, IN (US);
Jing Chen, Greenfield, IN (US);
Xin Zhang, Greenfield, IN (US);
Ping Huang, Greenfield, IN (US);
Assignee:
Elanco US Inc., Greenfield, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/04 (2006.01);
U.S. Cl.
CPC ...
C07D 413/04 (2013.01);
Abstract
The present disclosure provides processes for making enantiomerically pure isoxazoline compounds of formula (1), The present disclosure also provides processes for making enantiomerically pure isoxazoline compounds of formula (1) characterized by improving the enantiomeric purity of 3-methyl-5-[(5S)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4H-isoxazol-3-yl]thiophene-2-carboxylic acid by crystallization.