The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2025
Filed:
May. 26, 2020
Merck Sharp & Dohme Llc, Rahway, NJ (US);
Jacqueline D. Hicks, Watchung, NJ (US);
John S. Debenham, Scotch Plains, NJ (US);
Amjad Ali, Freehold, NJ (US);
Lan Wei, Berkeley Heights, NJ (US);
Tianying Jian, Westfield, NJ (US);
Dexi Yang, Livingston, NJ (US);
Anthony K. Ogawa, San Mateo, CA (US);
Wenlang Fu, Madison, NJ (US);
Matthew Lombardo, Flemington, NJ (US);
Rongze Kuang, Green Brook, NJ (US);
Meng Yang, Westfield, NJ (US);
Sung-Sau So, Verona, NJ (US);
Kenneth Ellsworth, Cranbury, NJ (US);
Peter Nizner, Fanwood, NJ (US);
Daniel A. Tatosian, Berkeley Heights, NJ (US);
Robert R. Wilkening, Maplewood, NJ (US);
Jun Wang, Avon, CT (US);
Merck Sharp & Dohme LLC, Rahway, NJ (US);
Abstract
The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XI activation inhibitors.