The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2025
Filed:
Jun. 25, 2019
Breath Therapeutics Gmbh, Munich, DE;
Oliver Denk, Muensing, DE;
Breath Therapeutics GmbH, Munich, DE;
Abstract
The present disclosure relates to a pharmaceutical composition comprising an inhalable immunosuppressive macrocyclic active ingredient for use in the prevention or treatment of a pulmonary disease or condition in a subject, wherein the pharmaceutical composition is administered to the subject by inhalation in form of an aerosol, and wherein the aerosol is generated by nebulization of the pharmaceutical composition using a nebulizer (), the nebulizer comprising: a) an aerosol generator () comprising: —a fluid reservoir () for holding the pharmaceutical composition or an interface configured to connect a fluid reservoir, and—a vibratable membrane () having a plurality of apertures, the apertures being adapted to produce an aerosol comprising droplets having a mass median aerodynamic diameter (MMAD) of up to about 15 4.0 μm as measured with a 0.9% (w/v) aqueous solution of sodium chloride; b) a chamber () for temporarily accommodating the aerosol generated by the aerosol generator (), the chamber having an inner lumen with a volume in the range of from about 50 to about 150 ml; and c) a mouthpiece () for delivering the aerosol supplied by the nebulizer () to the subject, the mouthpiece having an exhalation filter ().