The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2025
Filed:
Jun. 05, 2019
Medipost Co., Ltd., Seongnam-si, KR;
Yun Sun Yang, Seongnam-si, KR;
Wonil Oh, Seongnam-si, KR;
Soo Jin Choi, Seongnam-si, KR;
Jihye Kwak, Seongnam-si, KR;
Dong Hyon Kim, Seongnam-si, KR;
Hoon Lim, Seongnam-si, KR;
MEDIPOST CO., LTD, Seongnam-si, KR;
Abstract
A pharmaceutical composition comprising HLA-A2-expressing mesenchymal stem cells as an effective ingredient and its use in prevention or treatment of inflammatory disease are disclosed. The mesenchymal stem cells expressing HLA-A2 on the surface thereof inhibit the secretion of the inflammatory cytokine TNF-a and increase the expression of the anti-inflammatory markers CD163 and Arg-1, so that the pharmaceutical composition comprising the mesenchymal stem cells as an effective ingredient can be advantageously used for suppressing inflammation or treating inflammatory diseases.