The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2025
Filed:
Mar. 07, 2022
Applicant:
Msi-195 Holdings, Llc, Harrison, NY (US);
Inventors:
Dechi Guan, Vancouver, CA;
I. David MacDonald, Surrey, GB;
Assignee:
MSI-195 HOLDINGS, LLC, Harrison, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/7076 (2006.01); A61K 9/00 (2006.01); A61K 9/28 (2006.01); A61K 31/235 (2006.01); A61K 47/14 (2017.01); A61P 1/16 (2006.01); A61P 25/00 (2006.01); A61P 25/24 (2006.01); A61P 25/28 (2006.01); A61P 35/00 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7076 (2013.01); A61K 9/0053 (2013.01); A61K 9/28 (2013.01); A61K 31/235 (2013.01); A61K 47/14 (2013.01); A61P 1/16 (2018.01); A61P 25/00 (2018.01); A61P 25/24 (2018.01); A61P 25/28 (2018.01); A61P 35/00 (2018.01); A61K 9/2054 (2013.01); A61K 9/2059 (2013.01); A61K 9/4866 (2013.01);
Abstract
Provided herein are compositions and formulations comprising S-adenosyl-L-methionine ('SAM-e' or “SAMe”) and one or more gallic acid esters. Also provided herein are methods for improving the delivery of SAMe. Compositions and formulations provided herein increase SAMe plasma concentrations and area under the curve (AUC) values. Also provided herein are methods of treating a disease or disorder in a subject by administering compositions or formulations comprising exogenous SAMe and one or more gallic acid esters.