The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2025
Filed:
Sep. 22, 2017
Applicant:
The Johns Hopkins University, Baltimore, MD (US);
Inventors:
Marikki K. Laiho, Baltimore, MD (US);
Hester Hui Liu, Cockeysville, MD (US);
Paul Sirajuddin, Baltimore, MD (US);
Elina Ikonen, Baltimore, MD (US);
Assignee:
The Johns Hopkins University, Baltimore, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); A61K 31/17 (2006.01); A61K 31/18 (2006.01); A61K 31/416 (2006.01); A61K 31/437 (2006.01); A61K 31/4706 (2006.01); A61K 31/502 (2006.01); A61K 31/5025 (2006.01); A61K 31/519 (2006.01); A61K 31/675 (2006.01); A61K 35/00 (2006.01); A61K 38/00 (2006.01); A61K 38/55 (2006.01); A61K 45/06 (2006.01); A61P 35/02 (2006.01);
U.S. Cl.
CPC ...
A61K 31/517 (2013.01); A61K 31/17 (2013.01); A61K 31/18 (2013.01); A61K 31/416 (2013.01); A61K 31/437 (2013.01); A61K 31/4706 (2013.01); A61K 31/502 (2013.01); A61K 31/5025 (2013.01); A61K 31/519 (2013.01); A61K 31/675 (2013.01); A61K 35/00 (2013.01); A61K 38/005 (2013.01); A61K 38/55 (2013.01); A61K 45/06 (2013.01); A61P 35/02 (2018.01);
Abstract
Disclosed herein are compositions comprising a combination of at least one Pol I inhibitor, and at least one autophagy inhibiting compound, and/or at least one ACAT1 inhibiting compound, and/or at least one PARP inhibiting compound and their use in treating cancers and other related neoplastic diseases and which may also include additional chemotherapeutic agents.