The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 20, 2025

Filed:

Nov. 04, 2019
Applicant:

Intelgenx Corp., St-Laurent, CA;

Inventors:

Carolin Madwar, Montréal, CA;

Nadine Paiement, St-Laurent, CA;

Rodolphe Obeid, Pierrefonds, CA;

Justin W. Conway, Carignan, CA;

Erick Gonzalez-Labrada, Cote Saint-Luc, CA;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/47 (2006.01); A61K 9/00 (2006.01); A61K 9/107 (2006.01); A61K 31/352 (2006.01); A61K 47/44 (2017.01);
U.S. Cl.
CPC ...
A61K 31/47 (2013.01); A61K 9/006 (2013.01); A61K 9/107 (2013.01); A61K 31/352 (2013.01); A61K 47/44 (2013.01);
Abstract

Disclosed is a description and methods for formulating oral films containing lipophilic active ingredient(s), more particularly lipophilic active having a positive log P. The method involves dispersing the lipophilic active(s) in a carrier oil and uniformly distributing them as emulsified oil droplets into a polymer matrix. The methods reported here produce oral films containing a stable emulsion with up to 40% oil phase. The oil phase consists of the carrier oil and lipophilic active(s). This offers the possibility to enhance the amount of lipophilic actives to be included in the film formulation while preserving the film characteristics. The resulting oral films offer a standardized dosage form for lipophilic actives as well as easier and more convenient administration, transportation, handling, and storage.


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