The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2025
Filed:
Aug. 18, 2023
Applicant:
Nantcell, Inc., Culver City, CA (US);
Inventors:
Kayvan Niazi, Culver City, CA (US);
Jeffrey Safrit, Culver City, CA (US);
John H. Lee, Culver City, CA (US);
Assignees:
NantCell, Inc., Culver City, CA (US);
NantKwest, Inc., Dan Diego, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/167 (2006.01); A61K 31/192 (2006.01); A61K 31/215 (2006.01); A61K 31/4045 (2006.01); A61K 31/4406 (2006.01); A61K 31/506 (2006.01); A61K 35/17 (2025.01); A61K 38/20 (2006.01); A61K 39/00 (2006.01); A61K 39/12 (2006.01); A61K 39/395 (2006.01); A61K 40/11 (2025.01); A61K 40/15 (2025.01); A61K 40/31 (2025.01); A61K 40/46 (2025.01); C07K 14/735 (2006.01); C07K 16/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/167 (2013.01); A61K 31/192 (2013.01); A61K 31/215 (2013.01); A61K 31/4045 (2013.01); A61K 31/4406 (2013.01); A61K 31/506 (2013.01); A61K 38/2086 (2013.01); A61K 39/12 (2013.01); A61K 40/11 (2025.01); A61K 40/15 (2025.01); A61K 40/31 (2025.01); A61K 40/46 (2025.01); C07K 14/70535 (2013.01); C07K 16/1003 (2023.08); C07K 16/1063 (2013.01);
Abstract
HIV treatment, and especially treatment of latent infected CD4 cells, can be significantly improved using a kick-and-kill approach that employs an immune stimulation component and/or HDAC inhibition as one treatment component, and that may also include a second component in which a vaccine composition, various NK cells, CAR-T cells, and/or broadly neutralizing antibodies are administered.