The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2025
Filed:
May. 17, 2018
Takeda Pharmaceutical Company Limited, Osaka, JP;
Haruhide Kimura, Kanagawa, JP;
Yuu Sako, Kanagawa, JP;
Satoru Matsuda, Kanagawa, JP;
Yuji Shimizu, Kanagawa, JP;
Emi Kurimoto, Kanagawa, JP;
Takao Mandai, Kanagawa, JP;
Takeda Pharmaceutical Company Limited, Osaka, JP;
Abstract
The present invention provides a useful and efficient screening method for finding a cholinergic muscarinic M1 receptor positive allosteric modulator (M1PAM) with reduced cholinergic side effects. The present invention also provides a method for treating Alzheimer's disease and the like, a method for reducing cholinergic side effects, and the like which use M1PAM selected by the screening method and having a low α value, or the M1PAM and an acetylcholinesterase inhibitor.