The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 13, 2025

Filed:

Dec. 02, 2019
Applicants:

Wei-heng Shih, Bryn Mawr, PA (US);

Wan Y. Shih, Bryn Mawr, PA (US);

Giang AU, Sicklerville, NJ (US);

Ari D. Brooks, Cherry Hill, NJ (US);

Vanlila K. Swami, Philadelphia, PA (US);

Inventors:

Wei-Heng Shih, Bryn Mawr, PA (US);

Wan Y. Shih, Bryn Mawr, PA (US);

Giang Au, Sicklerville, NJ (US);

Ari D. Brooks, Cherry Hill, NJ (US);

Vanlila K. Swami, Philadelphia, PA (US);

Assignee:

Drexel University, Philadelphia, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); B82Y 15/00 (2011.01); C07K 16/22 (2006.01); C07K 16/30 (2006.01); G01N 33/532 (2006.01); G01N 33/533 (2006.01); G01N 33/551 (2006.01); G01N 33/58 (2006.01); B82Y 5/00 (2011.01); B82Y 40/00 (2011.01);
U.S. Cl.
CPC ...
G01N 33/57488 (2013.01); B82Y 15/00 (2013.01); C07K 16/22 (2013.01); C07K 16/30 (2013.01); G01N 33/532 (2013.01); G01N 33/533 (2013.01); G01N 33/551 (2013.01); G01N 33/574 (2013.01); G01N 33/57484 (2013.01); G01N 33/57492 (2013.01); G01N 33/588 (2013.01); B82Y 5/00 (2013.01); B82Y 40/00 (2013.01); G01N 2333/475 (2013.01); G01N 2333/705 (2013.01); G01N 2400/00 (2013.01); G01N 2458/00 (2013.01); Y10S 977/774 (2013.01); Y10S 977/824 (2013.01); Y10S 977/892 (2013.01); Y10S 977/927 (2013.01);
Abstract

One or more aqueous, near infrared emitting, high yield, highly photoluminescent, stable quantum dots conjugated to one or more biomarkers specific moieties. The conjugated quantum dots have an enhanced detection sensitivity and selectivity and may be formed using a novel and efficient method for conjugating one or more biomarker specific moieties to the quantum dots. The invention is further directed to a method for using the conjugated quantum dots for cancer detection in the margin of excised tissue.


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