The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 13, 2025

Filed:

Jun. 26, 2020
Applicant:

Polyanalytik Inc., London, CA;

Inventors:

Amer Ebied, London, CA;

Eric D. Landry, London, CA;

Peng Xiang, London, CA;

Solmaz Karamdoust, London, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/40 (2006.01); B01D 11/02 (2006.01); G01N 33/483 (2006.01);
U.S. Cl.
CPC ...
G01N 1/4055 (2013.01); B01D 11/0288 (2013.01); G01N 33/4833 (2013.01); B01D 2221/10 (2013.01); G01N 2001/4061 (2013.01);
Abstract

In general, this invention discloses methods for extracting and analyzing coatings from implanted and excised animal tissue medical devices; wherein the coating comprises at least one biodegradable polymer and at least one or more therapeutic ingredients. The present invention describes optimal conditions for extraction and isolation of biodegradable polymers and therapeutics in medical devices or complex pharmaceutical agent formulations prior and after implanting or injecting into animal tissues. Particularly this work relates to accurate isolation and quantification of ppm amounts of polymer and/or therapeutics without biological interferences. The use of GPC/SEC systems equipped with light scattering detectors enables 'absolute' or “true” molecular weight determination. All of these improvements allow for accurate determination of the degradation profile of the polymer/therapeutic component independent of polymer standards used in conventional GPC/SEC.


Find Patent Forward Citations

Loading…