The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 13, 2025

Filed:

Jun. 19, 2023
Applicant:

Roche Sequencing Solutions, Inc., Pleasanton, CA (US);

Inventors:

Randall W. Davis, Pleasanton, CA (US);

Edward Shian Liu, Saratoga, CA (US);

Eric Takeshi Harada, San Jose, CA (US);

Anne Aguirre, San Jose, CA (US);

Andrew Trans, Mountain View, CA (US);

James Pollard, Mountain View, CA (US);

Cynthia Cech, Newcastle, WA (US);

Assignee:

Roche Sequencing Solutions, Inc., Pleasanton, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6869 (2018.01); C12M 1/34 (2006.01); G01N 27/327 (2006.01); G01N 27/447 (2006.01); G01N 33/487 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6869 (2013.01); C12M 1/34 (2013.01); G01N 27/3277 (2013.01); G01N 27/3278 (2013.01); G01N 27/44791 (2013.01); G01N 33/48721 (2013.01);
Abstract

This disclosure provides a biochip comprising a plurality of wells. The biochip includes a membrane that is disposed in or adjacent to an individual well of the plurality of wells. The membrane comprises a nanopore, and the individual well comprises an electrode that detects a signal upon ionic flow through the pore in response to a species passing through or adjacent to the nanopore. The electrode can be a non-sacrificial electrode. A lipid bilayer can be formed over the plurality of wells using a bubble.


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