The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2025
Filed:
Oct. 19, 2023
Applicant:
Agsino Gensources Co., Ltd., Shenzhen, CN;
Assignee:
AGSINO GENSOURCES CO., LTD., Shenzhen, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/48 (2006.01); A01K 67/0275 (2024.01); C07H 21/04 (2006.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C12N 9/485 (2013.01); A01K 67/0275 (2013.01); C07H 21/04 (2013.01); C12N 15/907 (2013.01); C12Y 304/11002 (2013.01); A01K 2217/05 (2013.01); A01K 2227/108 (2013.01); C12N 2310/20 (2017.05);
Abstract
The present invention provides a pAPN mutant and a composition for site-directed modification of pAPN gene and application thereof, involving the field of gene editing technology. The mutated pAPN mutant with an alanine at position 734 can maintain its normal expression, while reducing the ability of a host expressing the pAPN mutant to specifically bind to TGEV, which has important scientific and practical significance in pig disease resistance breeding.