The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2025
Filed:
Aug. 08, 2024
Applicant:
Beijing Friendship Hospital, Capital Medical University, Beijing, CN;
Inventors:
Assignee:
Beijing Friendship Hospital, Capital Medical University, Beijing, CN;
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 31/519 (2006.01); A61K 31/7105 (2006.01); A61K 31/713 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1137 (2013.01); A61K 31/519 (2013.01); A61K 31/7105 (2013.01); C12Y 207/01091 (2013.01); C12Y 301/04012 (2013.01); C12N 2310/531 (2013.01); C12N 2320/31 (2013.01);
Abstract
A biomarker for predicting drug resistance of a BTK inhibitor and an application thereof are provided in the present disclosure, relating to the technical field of biomedicine. The biomarker is SMPD1 or SPHK1; the drug resistance of BTK inhibitor refers to the drug resistance of diffuse large B cell lymphom cells to the BTK inhibitor. This biomarker is used to predict sensitivity of diffuse large B cell lymphom cells to the BTK inhibitors.