The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2025
Filed:
Jul. 31, 2019
Applicant:
Yale University, New Haven, CT (US);
Inventors:
Sidi Chen, Milford, CT (US);
Lupeng Ye, New Haven, CT (US);
Jonathan Park, Scott AFB, IL (US);
Matthew Dong, San Francisco, CA (US);
Ryan D. Chow, San Jose, CA (US);
Assignee:
Yale University, New Haven, CT (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/42 (2025.01); C12N 15/11 (2006.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C12N 15/111 (2013.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/42 (2025.01); A61K 40/4204 (2025.01); C12N 15/90 (2013.01); A61K 2239/31 (2023.05); A61K 2239/47 (2023.05); C12N 2310/20 (2017.05); C12N 2800/90 (2013.01); C12Y 204/01155 (2013.01); C12Y 503/04001 (2013.01);
Abstract
The present invention includes compositions and methods for identification of membrane targets for enhancement of T cell activity against a disease, disorder or condition, and/or enhancing T cell anti-tumor activity in a subject in need thereof. In some embodiments, the disease is cancer. In further embodiments, the cancer is glioblastoma (GBM) or breast cancer.