The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 13, 2025

Filed:

Aug. 29, 2022
Applicant:

Futu Biotech Co., Ltd., Wuhan, CN;

Inventors:

Bo Hu, Wuhan, CN;

Yanan Li, Wuhan, CN;

Hao Wang, Beijing, CN;

Lei Wang, Beijing, CN;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); A61K 47/54 (2017.01); A61P 9/14 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61K 47/543 (2017.08); A61P 9/14 (2018.01); A61K 38/00 (2013.01);
Abstract

A nano small peptide FH and its use in preparation of drugs for treating and preventing fundus vascular diseases are provided. The artificially synthesized nano small peptide has a molecular formula of X-FFVLK-KQKRPRH (SEQ ID NO:), wherein the X is dodecanoyl, tetradecanoyl, hexadecanoyl, or octadecanoyl. The nano small peptide of the present invention can specifically select receptors to encapsulate sSemaD protein, and the concentration of sSemaD is effectively reduced, so that the sSemaD is unable to bind to any receptors, thus changing the shortcoming of few inhibitory targets of antibody drugs. The nano small peptide molecule with a simple structure can be mixed with antibody drugs without causing mutual immune reactions, so as to achieve the effect of reducing multiple pro-angiogenesis molecules.


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