The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 13, 2025

Filed:

Jul. 31, 2020
Applicants:

Jiangsu Simcere Pharmaceutical Co., Ltd., Nanjing, CN;

Simcere Bio-pharmaceutical Technology., Ltd., Nanjing, CN;

Inventors:

Xinyan Zhao, Nanjing, CN;

Xiaofeng Zhao, Nanjing, CN;

Shiqiang Lu, Nanjing, CN;

Ran Pang, Nanjing, CN;

Xinxin Li, Nanjing, CN;

Jinsheng Ren, Nanjing, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61P 35/00 (2006.01); G01N 33/574 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); A61P 35/00 (2018.01); C07K 16/2818 (2013.01); C07K 16/2827 (2013.01); G01N 33/57492 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/24 (2013.01); C07K 2317/34 (2013.01); C07K 2317/732 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); G01N 2333/7151 (2013.01);
Abstract

Provided is an antibody or an antigen-binding fragment thereof capable of specifically binding to TNFR2, wherein the antibody or the antigen-binding fragment thereof is capable of regulating the function of immune cells and may be used as a medicament to treat diseases related to immune-related disorders, such as tumors. A polynucleotide encoding the antibody or antigen-binding fragment thereof and a pharmaceutical composition comprising the antibody or antigen binding fragment thereof are also provided.


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