The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 13, 2025

Filed:

Aug. 01, 2023
Applicants:

Kyowa Kirin Co., Ltd., Tokyo, JP;

Kagoshima University, Kagoshima, JP;

Inventors:

Nobuaki Takahashi, Tokyo, JP;

Ryosuke Nakano, Tokyo, JP;

Sayaka Maeda, Tokyo, JP;

Yuji Ito, Kagoshima, JP;

Assignees:

KYOWA KIRIN CO., LTD., Tokyo, JP;

KAGOSHIMA UNIVERSITY, Kagoshima, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 47/10 (2017.01); A61K 47/36 (2006.01); C12N 5/12 (2006.01); G01N 33/563 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61K 47/10 (2013.01); A61K 47/36 (2013.01); C12N 5/12 (2013.01); G01N 33/563 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/565 (2013.01);
Abstract

The invention relates to an antibody which binds to myelin oligodendrocyte glycoprotein (MOG), an antibody fragment thereof, a hybridoma which produces the antibody or the antibody fragment, a nucleic acid containing a nucleotide sequence which encodes the antibody or the antibody fragment, a transformant cell containing a vector containing the nucleic acid, a method for producing the antibody or the antibody fragment, a composition containing the antibody or the antibody fragment and a method for detecting or measuring an antigen that is present in the brain, a method for diagnosing or treating a brain disease, a method for improving the property of an antibody of accumulating in the brain and a method for increasing the amount of an antibody in the brain which use the antibody or the antibody fragment.


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