The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 13, 2025

Filed:

Oct. 02, 2019
Applicants:

Georg-august-universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin, Göttingen, DE;

Lifearc, London, GB;

Inventors:

Thomas Bayer, Göttingen, DE;

Preeti Bakrania, Harrow, GB;

Sarah Davies, Stevenage, GB;

Alex Brown, Chesham, GB;

Chido Mpamhanga, Harpenden, GB;

David Matthews, Hitchin, GB;

Mark Carr, Leicester, GB;

Gareth Hall, Leicester, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); A61P 25/28 (2006.01); G01N 33/68 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61P 25/28 (2018.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/567 (2013.01);
Abstract

The present invention relates to humanised antibodies that bind amyloid peptides, which antibodies comprise mutations in the heavy chain and/or light chain variable domains, which mutations improve the binding activity. The antibodies may be useful in the treatment of Alzheimer's disease (AD).


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