The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2025
Filed:
Jul. 16, 2019
Humabs Biomed SA, Bellinzona, CH;
Institute for Research IN Biomedicine, Bellinzona, CH;
Matteo Samuele Pizzuto, Bellinzona, CH;
Fabio Benigni, Bellinzona, CH;
Davide Corti, Bellinzona, CH;
Fabio Grassi, Bellinzona, CH;
Lisa Perruzza, Bellinzona, CH;
Humabs BioMed SA, Bellinzona, CH;
Institute for Research in Biomedicine, Bellinzona, CH;
Abstract
The instant disclosure provides antibodies and antigen-binding fragments thereof that are specific forand, in certain embodiments, are capable of neutralizing ainfection in a subject. In certain embodiments, the antibody or antigen binding fragment comprises an IgA antibody, such as, for example, a secretory IgA antibody. Also provided are pharmaceutical compositions comprising a disclosed antibody or antigen-binding fragment. Methods of using the antibodies, antigen-binding fragments, and compositions to treat or prevent ainfection in a subject are also provided. In certain embodiments, recombinant secretory IgA antibodies of the instant disclosure are administered orally to a subject having or at risk of developing ainfection.