The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2025
Filed:
Jun. 22, 2021
Applicant:
Immatics Biotechnologies Gmbh, Tuebingen, DE;
Inventors:
Sebastian Bunk, Tuebingen, DE;
Dominik Maurer, Moessingen, DE;
Jens Fritsche, Dusslingen, DE;
Claudia Wagner, Tuebingen, DE;
Leonie Alten, Tuebingen, DE;
Franziska Hoffgaard, Tuebingen, DE;
Mathias Ferber, Paris, FR;
Assignee:
Immatics Biotechnologies GmbH, Tübingen, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/725 (2006.01); A61K 35/17 (2015.01); C12N 5/0783 (2010.01); C12N 15/09 (2006.01);
U.S. Cl.
CPC ...
C07K 14/7051 (2013.01); A61K 35/17 (2013.01); C12N 5/0636 (2013.01); C12N 5/0638 (2013.01); C12N 15/09 (2013.01); C12N 2501/515 (2013.01); C12N 2510/00 (2013.01);
Abstract
The present invention relates to modified T cell receptor (TCR) α or β chains, or heterodimers comprising the same, wherein in the variable domain of said modified α or β chain, an amino acid at position 44 according to the IMGT numbering is substituted by another suitable amino acid in order to improve pairing of desired chains.