The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2025
Filed:
Dec. 21, 2018
Centro DE Ingeniería Genética Y Biotecnología, Havana, CU;
Yunier Rodriguez Alvarez, Artemisa, CU;
Hilda Elisa Garay Perez, Havana, CU;
Osvaldo Reyes Acosta, Havana, CU;
Ania Cabrales Rico, Havana, CU;
CENTRO DE INGENIERÍA GENÉTICA Y BIOTECNOLOGÍA, Havana, CU;
Abstract
The present invention discloses an antagonist peptide of the Interleukin-15 (IL-15) activity, which is characterized in that it comprises an amino acid sequence identified as SEQ ID No. 5 or SEQ ID No. 12, or a homodimer of these peptides, as well as a nucleic acid that encodes for the peptide with the sequence identified as SEQ ID No. 5 or SEQ ID No. 12. Pharmaceutical compositions comprising said peptides or nucleic acids encoding said sequences are part of the invention. In addition, it provides the use of an IL-15 antagonist peptide comprising the amino acid sequence identified as SEQ ID No. 5 or SEQ ID No. 12, or a homodimer of these peptides, for the manufacture of a medicament. The invention contemplates a method for the treatment of a disease related to the IL-15 overexpression, prostate and kidney cancer.