The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 13, 2025

Filed:

Nov. 21, 2023
Applicant:

Neuren Pharmaceuticals Limited, Auckland, NZ;

Inventors:

Clive Blower, Doncaster East, AU;

Matthew Peterson, San Diego, CA (US);

James Murray Shaw, Parkdale, AU;

James Anthony Bonnar, Ryde, AU;

Etienne David Frank Philippe Moniotte, Waterloo, BE;

Martin Bernard Catherine Bousmanne, Woluwe Saint-Lambert, BE;

Cecilia Betti, Brussels, BE;

Karel Willy Luc Decroos, Ghent, BE;

Mimoun Ayoub, Staefa, CH;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/16 (2006.01); B01J 21/06 (2006.01); B01J 21/18 (2006.01); B01J 23/44 (2006.01);
U.S. Cl.
CPC ...
C07D 207/16 (2013.01); B01J 21/06 (2013.01); B01J 21/18 (2013.01); B01J 23/44 (2013.01); C07B 2200/07 (2013.01);
Abstract

This disclosure describes compounds of Formula (I), stereoisomers, side compounds thereof, pharmaceutical compositions and methods of manufacturing such compounds, using silylation reagents and producing compositions and products made using such methods. More particularly, this disclosure describes manufacture of trofinetide and side products, compositions and products containing such compounds, for pharmaceutical uses to treat neurodegenerative or neurodevelopmental disorders.


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