Microparticle sorting device, cell therapeutic agent manufacturing device, microparticle sorting method and program

Abstract

Provided is a technology for preparing a mixture including multiple types of microparticles in accordance with a predetermined ratio. The present technology provides a microparticle sorting device () including a control unit () comprising a determination unit that determines whether microparticles are sorted, on the basis of light generated by irradiating, with light, the microparticles flowing through a flow channel (), in which the determination unit performs a primary sorting determination to determine, on the basis of characteristics of the light generated, whether the microparticles belong to any one of two or more different microparticle populations, and then performs a secondary sorting determination to determine whether the microparticles determined to belong to any one of the microparticle populations in the primary sorting determination are sorted, on the basis of the particle constituent ratio specified for the two or more different microparticle populations. This technology may be used to prepare a cell therapeutic agent comprising a mixture of cells of different types in a predefined ratio, e.g. a mixture of various types of CAR T-cells showing a synergistic anti-tumor activity.