The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2025
Filed:
Dec. 19, 2019
Evolved BY Nature, Inc., Medford, MA (US);
Gregory H. Altman, Providence, RI (US);
Rebecca L. Lacouture, Needham, MA (US);
Peng Xu, Lexington, MA (US);
Erlei Jin, Winchester, MA (US);
Carlos J. Bosques, Arlington, MA (US);
Patrick Yacono, Medford, MA (US);
Patrik Johansson, Medford, MA (US);
EVOLVED BY NATURE, INC., Needham, MA (US);
Abstract
Hyaluronic acid and silk fibroin or silk fibroin fragments tissue fillers and methods of making and using the same are provided herein. In some embodiments, the disclosure relates to a biocompatible tissue filler comprising silk fibroin or silk fibroin fragments, hyaluronic acid (HA), and polyethylene glycol (PEG) and/or polypropylene glycol (PPG), wherein a portion of the HA is modified or crosslinked by one or more linker moieties comprising one or more of polyethylene glycol (PEG), polypropylene glycol (PPG), and a secondary alcohol, wherein the linker moieties are attached to the HA at one end of the linker.