The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 13, 2025

Filed:

Oct. 26, 2021
Applicant:

The Governors of the University of Alberta, Edmonton, CA;

Inventors:

Michael Houghton, Danville, CA (US);

Abdolamir Landi, Edmonton, CA;

Michael Logan, Edmonton, CA;

John L. Law, Edmonton, CA;

Darren Hockman, Edmonton, CA;

Chao Chen, Edmonton, CA;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/29 (2006.01); A61K 39/00 (2006.01); A61K 39/12 (2006.01); A61K 39/39 (2006.01); A61P 31/14 (2006.01);
U.S. Cl.
CPC ...
A61K 39/29 (2013.01); A61K 39/12 (2013.01); A61K 2039/53 (2013.01); A61K 2039/54 (2013.01); A61K 2039/55544 (2013.01); A61K 2039/70 (2013.01); C12N 2710/10034 (2013.01); C12N 2710/10043 (2013.01); C12N 2710/24134 (2013.01); C12N 2710/24143 (2013.01); C12N 2770/24234 (2013.01);
Abstract

The present disclosure provides an immunogenic composition comprising: a) a hepatitis C virus (HCV) heterodimeric polypeptide that includes HCV E1 and E2 polypeptides; b) a T-cell epitope polypeptide comprising a T-cell epitope present in an HCV protein other than E1 and E2; and c) a pharmaceutically acceptable excipient. The present disclosure provides a method of inducing an immune response, in an individual, to an HCV polypeptide. The present disclosure provides an immunogenic composition comprising: a) a polypeptide that comprises one or more T-cell epitopes present in an HCV protein other than E1 and E2; and b) a pharmaceutically acceptable excipient.


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