The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2025
Filed:
Jan. 17, 2023
Applicants:
Amgen Inc., Thousand Oaks, CA (US);
Cytokinetics, Inc., South San Francisco, CA (US);
Inventors:
Narimon Honarpour, Thousand Oaks, CA (US);
Fady Malik, South San Francisco, CA (US);
Assignees:
CYTOKINETICS, INC., South San Francisco, CA (US);
AMGEN INC., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 9/00 (2006.01); A61P 9/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); A61K 9/0053 (2013.01); A61P 9/04 (2018.01);
Abstract
Provided herein are methods of treating a subject with heart failure, comprising administering to the subject an initial dose of a cardiac sarcomere activator (CSA) for an initial time period, and subsequently administering to the subject a dose of the CSA based on the subject's plasma concentration of the CSA at the end of the initial time period.