The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 13, 2025

Filed:

Mar. 16, 2023
Applicant:

Mie University, Tsu, JP;

Inventors:

Toshiyuki Shibata, Tsu, JP;

Hideo Miyake, Tsu, JP;

Reiji Tanaka, Tsu, JP;

Fumino Okuda, Tsu, JP;

Mano Hasegawa, Tsu, JP;

Assignee:

MIE UNIVERSITY, Tsu, JP;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/7004 (2006.01); A61K 31/047 (2006.01); A61K 38/18 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
A61K 31/047 (2013.01); A61K 38/185 (2013.01); A61P 25/28 (2018.01);
Abstract

A method of treating a patient in need thereof includes administering a therapeutically effective amount of 4-deoxy-L-erythro-5-hexoseulose uronic acid (DEH) to serve or function as a nerve growth factor (NGF) activity promoter, preferably to treat and/or prevent a neurodegenerative disease, such as PolyQ disease, Parkinson's disease, Parkinson's syndrome, spinocerebellar degeneration, spastic paraplegia, amyotrophic lateral sclerosis, Alzheimer's disease, dementia with Lewy bodies or corticobasal degeneration.


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