The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 06, 2025

Filed:

May. 08, 2019
Applicant:

Sigma-aldrich Co. Llc, St. Louis, MO (US);

Inventors:

Kevin B. Ray, Ballwin, MO (US);

Pegah Jalili, St. Louis, MO (US);

Jeffrey L. Turner, Maryville, IL (US);

Nicolas Caffarelli, St. Louis, MO (US);

Yue Lu, St. Louis, MO (US);

Assignee:

Sigma-Aldrich Co. LLC, St. Louis, MO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2005.12); G01N 30/02 (2005.12); G01N 33/538 (2005.12); G01N 33/549 (2005.12); G01N 33/563 (2005.12); G01N 33/68 (2005.12);
U.S. Cl.
CPC ...
G01N 33/6848 (2012.12); G01N 30/02 (2012.12); G01N 33/538 (2012.12); G01N 33/549 (2012.12); G01N 33/563 (2012.12); G01N 2030/027 (2012.12); G01N 2333/976 (2012.12);
Abstract

Methods and kits for detecting and/or quantitating target proteins in biological samples. In particular, the method comprises capture and immobilization of the target protein, protein denaturation, proteolytic digestion, and analysis using a mass spectrometry-based technique.


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