The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 2025
Filed:
Apr. 24, 2015
Applicant:
2seventy Bio, Inc., Cambridge, MA (US);
Inventors:
Richard Morgan, Center Harbor, NH (US);
Kevin Friedman, Medford, MA (US);
Dawn Maier, North Reading, MA (US);
Assignee:
2seventy bio, Inc., Cambridge, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/0783 (2009.12); A61K 35/12 (2014.12); A61K 38/17 (2005.12); A61K 39/00 (2005.12); C12N 7/00 (2005.12); C12N 15/86 (2005.12);
U.S. Cl.
CPC ...
C12N 5/0636 (2012.12); A61K 38/177 (2012.12); A61K 39/4611 (2023.04); A61K 39/4631 (2023.04); A61K 39/464412 (2023.04); A61K 39/464417 (2023.04); C12N 7/00 (2012.12); C12N 15/86 (2012.12); A61K 2035/124 (2012.12); C07K 2319/00 (2012.12); C12N 2501/2301 (2012.12); C12N 2501/998 (2012.12); C12N 2740/10043 (2012.12); C12N 2740/15043 (2012.12); C12N 2799/021 (2012.12); C12N 2799/027 (2012.12); C12N 2810/855 (2012.12);
Abstract
The invention provides compositions and methods for manufacturing adoptive cell therapies. In particular embodiments, the invention provides methods of harvesting populations of cells, isolating and activating PBMCs, expanding T cells, and administering the T cell therapeutic to a subject in need thereof.