The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 2025
Filed:
Feb. 10, 2020
Applicant:
Yeda Research and Development Co. Ltd., Rehovot, IL;
Inventors:
Irit Sagi, Rehovot, IL;
Vishnu Mohan, Rehovot, IL;
Assignee:
Yeda Research and Development Co. Ltd., Rehovot, IL;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2005.12); A61K 31/282 (2005.12); A61K 31/7068 (2005.12); A61K 39/00 (2005.12); A61P 35/00 (2005.12); C07K 16/30 (2005.12);
U.S. Cl.
CPC ...
C07K 16/40 (2012.12); A61K 31/282 (2012.12); A61K 31/7068 (2012.12); A61K 39/00 (2012.12); A61P 35/00 (2017.12); C07K 16/303 (2012.12); A61K 2039/505 (2012.12); C07K 2317/34 (2012.12); C07K 2317/55 (2012.12); C07K 2317/565 (2012.12); C07K 2317/73 (2012.12); C07K 2317/76 (2012.12); C07K 2317/92 (2012.12);
Abstract
A method of treating a disease associated with imbalanced or abnormal activity of MMP-7 is diclosed. The method comprises administration of an antibody comprising an antigen recognition region which binds a catalytic site of MMP-7, having complementarity determining region amino acid sequences as set forth in: SEQ ID NOs: 3, 4 and 5 (CDR3), sequentially arranged from N to C on a light chain of the antibody; and SEQ ID NOs: 6, 7 and 8, sequentially arranged from N to C on a heavy chain of the antibody.