The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 2025
Filed:
Oct. 20, 2023
Applicant:
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Inventors:
David DiLillo, Tarrytown, NY (US);
Thomas Craig Meagher, Tarrytown, NY (US);
Assignee:
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/725 (2005.12); A61K 38/00 (2005.12); A61K 39/00 (2005.12); A61K 40/11 (2024.12); A61K 40/31 (2024.12); A61K 40/42 (2024.12); C07K 14/705 (2005.12); C12N 5/0783 (2009.12);
U.S. Cl.
CPC ...
C07K 14/7051 (2012.12); A61K 40/11 (2024.12); A61K 40/31 (2024.12); A61K 40/4245 (2024.12); A61K 40/4268 (2024.12); A61K 40/4269 (2024.12); C07K 14/70517 (2012.12); C07K 14/70521 (2012.12); C07K 14/70578 (2012.12); C12N 5/0638 (2012.12); A61K 38/00 (2012.12); A61K 2239/31 (2023.04); A61K 2239/38 (2023.04); A61K 2239/57 (2023.04); C07K 2319/03 (2012.12); C07K 2319/30 (2012.12);
Abstract
Disclosed are compositions and methods for targeted treatment of cancer. The present disclosure provides chimeric antigen receptors and cells expressing such chimeric antigen receptors. In certain embodiments, engineered cells expressing the chimeric antigen receptors are specific for a low density cancer antigen or peptide in groove antigen.