The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 2025
Filed:
May. 11, 2022
Novocure Gmbh, Root, CH;
Carsten Hagemann, Unterpleichfeld, DE;
Mario Lohr, Dillenburg, DE;
Almuth F. Kessler, Reichenberg, DE;
Malgorzata Burek, Wurzburg, DE;
Carola Forster, Wurzburg, DE;
Catherine Brami, Matan, IL;
Hadas Sara Hershkovich, Kiryat Motzkin, IL;
Tali Voloshin-Sela, Haifa, IL;
Novocure Gmbh, Baar, CH;
Abstract
Certain substances (e.g., large molecules) that ordinarily cannot traverse the blood brain barrier can be introduced into the brain by applying an alternating electric field to the brain for a period of time, wherein the frequency of the alternating electric field is selected so that application of the alternating electric field increases permeability of the blood brain barrier. In some embodiments, the frequency of the alternating electric field is less than 190 kHz (e.g., 100 kHz). Once the permeability of the blood brain barrier has been increased, the substance is able to cross the blood brain barrier.