The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 2025
Filed:
May. 08, 2020
Applicant:
Synthon B.v., Nijmegen, NL;
Inventors:
Manuel Gago Guillan, Sant Boi de Llobregat, ES;
Rohit Kumar, Sant Boi de Llobregat, ES;
Lisardo Alvarez Fernandez, Sant Boi de Llobregat, ES;
Assignee:
Synthon B.V., Nijmegen, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/20 (2005.12); A61K 9/28 (2005.12); A61K 31/4439 (2005.12); A61P 35/00 (2005.12);
U.S. Cl.
CPC ...
A61K 9/20 (2012.12); A61K 9/2009 (2012.12); A61K 9/2018 (2012.12); A61K 9/2027 (2012.12); A61K 9/2054 (2012.12); A61K 9/2059 (2012.12); A61K 9/28 (2012.12); A61K 31/4439 (2012.12); A61P 35/00 (2017.12);
Abstract
The present invention relates to an immediate release tablet composition comprising axitinib form IV characterized by an XRPD pattern comprising the peaks at about 8.9, 12.0, 14.6, 15.2, 15.7, 17.8, 19.1, 20.6, 21.6, 23.2, 24.2, 24.9, 26.1 and 27.5±0.1 degrees 2θ, when measured with Cu Kα1 radiation and one or more pharmaceutically acceptable excipients, wherein the composition exhibits a dissolution rate between 40% and 70% in 30 minutes when tested in 900 ml 0.01 N hydrochloric acid pH 2.0 at 37° C., 75 rpm in a USP apparatus II.