The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 2025
Filed:
Jul. 26, 2022
Applicant:
Bracco Imaging S.p.a., Milan, IT;
Inventors:
Andrea Banin, Collegno, IT;
Andrea Barale, Bibiana, IT;
Valeria Boi, Strambino, IT;
Sonia Gazzetto, Cascinette d'Ivrea, IT;
Federica Buonsanti, Turin, IT;
Assignee:
BRACCO IMAGING S.P.A., Milan, IT;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/055 (2005.12); A61K 49/10 (2005.12);
U.S. Cl.
CPC ...
A61K 49/106 (2012.12);
Abstract
The invention relates to a process for the preparation of dimeric contrast agents for use in Magnetic resonance Imaging (MRI), in particular [μ-[1-[bis[2-(hydroxy-κO)-3-[4,7,10-tris[(carboxy-κO)methyl]-1,4,7,10-tetraazacyclododec-1-yl-κN,κN,κN,κN]propyl]amino]-1-deoxy-D-glucitolate(6-)]]di-gadolinium complex, which includes preparation steps carried out one-pot (without isolation of the obtained intermediate) and precipitation of at least part of free gadolinium metal ions in excess.