The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 2025
Filed:
Aug. 23, 2019
Applicant:
Spark Therapeutics, Inc., Philadelphia, PA (US);
Inventors:
Xavier Anguela, Barcelona, ES;
Liron Elkouby, Modi'in-Maccabim-Reut, IL;
Assignee:
Spark Therapeutics, Inc., Philadelphia, PA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2005.12); A61K 9/00 (2005.12); A61P 7/04 (2005.12); C07K 14/755 (2005.12); C07K 14/775 (2005.12); C07K 14/81 (2005.12); C12N 7/00 (2005.12); C12N 15/86 (2005.12); A61K 38/00 (2005.12);
U.S. Cl.
CPC ...
A61K 48/0066 (2012.12); A61K 9/0019 (2012.12); A61K 48/0058 (2012.12); A61P 7/04 (2017.12); C07K 14/755 (2012.12); C07K 14/775 (2012.12); C07K 14/8125 (2012.12); C12N 7/00 (2012.12); C12N 15/86 (2012.12); A61K 38/00 (2012.12); C07K 2319/00 (2012.12); C12N 2750/14143 (2012.12); C12N 2800/22 (2012.12);
Abstract
The disclosure includes CpG reduced regulatory elements, polynucleotides comprising such CpG reduced regulatory elements, expression cassettes comprising such CpG reduced regulatory elements, and recombinant AAV vectors comprising such CpG reduced regulatory elements. The regulatory elements can be, for example, operably coupled to a transgene.