The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 06, 2025

Filed:

Mar. 25, 2021
Applicant:

Wisconsin Alumni Research Foundation (Warf), Madison, WI (US);

Inventors:

Yoshihiro Kawaoka, Middleton, WI (US);

Gabriele Neumann, Madison, WI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/295 (2005.12); A61K 39/145 (2005.12); A61K 39/215 (2005.12); A61P 31/14 (2005.12); A61P 31/16 (2005.12); C07K 14/005 (2005.12); C12N 7/00 (2005.12); A61K 39/00 (2005.12);
U.S. Cl.
CPC ...
A61K 39/295 (2012.12); A61K 39/145 (2012.12); A61K 39/215 (2012.12); A61P 31/14 (2017.12); A61P 31/16 (2017.12); C07K 14/005 (2012.12); C12N 7/00 (2012.12); A61K 2039/5254 (2012.12); A61K 2039/5256 (2012.12); A61K 2039/55 (2012.12); A61K 2039/70 (2012.12); C07K 2319/03 (2012.12); C12N 2760/16121 (2012.12); C12N 2760/16122 (2012.12); C12N 2760/16134 (2012.12); C12N 2760/16171 (2012.12); C12N 2770/18021 (2012.12); C12N 2770/18022 (2012.12); C12N 2770/18034 (2012.12); C12N 2770/18071 (2012.12);
Abstract

The invention provides a composition useful to prepare influenza vaccine viruses, e.g., in the absence of helper virus, which includes internal viral segments from an influenza virus vaccine strain or isolate, e.g., one that is safe in humans, for instance, one that does not result in significant disease, and encodes a heterologous antigen.


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